CALCINEURIN (PP2B) SUBSTRATE [DLDVPIPGRFDRRVSSVAAE], NON-PHOSPHORYLATED
Calcineurin Substrate
CAS: 113873-67-9
Molecular Formula: C92H150N28O29
CALCINEURIN (PP2B) SUBSTRATE [DLDVPIPGRFDRRVSSVAAE], NON-PHOSPHORYLATED - Names and Identifiers
CALCINEURIN (PP2B) SUBSTRATE [DLDVPIPGRFDRRVSSVAAE], NON-PHOSPHORYLATED - Physico-chemical Properties
| Molecular Formula | C92H150N28O29 |
| Molar Mass | 2112.35 |
| Density | 1.49±0.1 g/cm3(Predicted) |
| Appearance | White powder. |
| Storage Condition | −20°C |
| In vitro study | Calcineurin (PP2B), a serine/threonine phosphatase controlled by cellular calcium, has been implicated in a wide variety of biological responses including lymphocyte activation, neuronal and muscle development, neurite outgrowth, and morphogenesis of vertebrate heart valves. |
CALCINEURIN (PP2B) SUBSTRATE [DLDVPIPGRFDRRVSSVAAE], NON-PHOSPHORYLATED - Risk and Safety
| WGK Germany | 3 |
CALCINEURIN (PP2B) SUBSTRATE [DLDVPIPGRFDRRVSSVAAE], NON-PHOSPHORYLATED - Reference Information
| introduction | calcineurin is the only calcium and calmodulin-dependent phosphoprotein phosphatase rich in mammalian brain. The enzyme (calcineurin,CaN) is also distributed in extracellular tissues such as sperm cells, lymphocytes and muscle tissues, but the content is far lower than that of the brain. CaN consists of a regulatory subunit bound by 18kDCa2 + and a catalytic subunit bound by 61kD calmodulin. In addition to binding to Ca2 +, the enzyme can also bind to metal ions such as Mn2 +, Ni2 +, Co2 + and affect its activity. |
| source distribution | immunohistochemical localization shows that it is mainly distributed in striatum, hippocampus, cerebral cortex and other regions of the brain. in each brain region, various isozymes of CaN are expressed differently in specific neuron subsets. this regional expression of CaN may be related to the specificity of different calcineurin substrates. |
| Biological activity | Calcineurin substrate are polypeptides from the cAMP-dependent protein kinase regulatory RII subunit. Calcineurin substrate can be used to determine the activity of calcineurin. |
| in vitro research | Calcineurin (PP2B), a serine/threonine phosphatase controlled by cellular calcium, has been implicated in a wide variety of biological responses including lymphocyte activation, neuronal and muscle development, neurite outgrowth, and morphogenesis of vertebrate heart valves. |
Last Update：2024-04-10 22:29:15
![CALCINEURIN (PP2B) SUBSTRATE [DLDVPIPGRFDRRVSSVAAE], NON-PHOSPHORYLATED](http://res.chembk.com/assets/images/structure/113873-67-9.gif)
Supplier List
Spot supply
Product Name: Calcineurin Substrate Request for quotationCAS: 113873-67-9
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Calcineurin Substrate Visit Supplier Webpage Request for quotationCAS: 113873-67-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Calcineurin Substrate Visit Supplier Webpage Request for quotationCAS: 113873-67-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: PKA RII peptide Visit Supplier Webpage Request for quotationCAS: 113873-67-9
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Calcineurin substrate Visit Supplier Webpage Request for quotationCAS: 113873-67-9
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Product Name: Calcineurin Substrate Visit Supplier Webpage Request for quotation
CAS: 113873-67-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 113873-67-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: Calcineurin Substrate Request for quotationCAS: 113873-67-9
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Calcineurin Substrate Visit Supplier Webpage Request for quotationCAS: 113873-67-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Calcineurin Substrate Visit Supplier Webpage Request for quotationCAS: 113873-67-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: PKA RII peptide Visit Supplier Webpage Request for quotationCAS: 113873-67-9
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Calcineurin substrate Visit Supplier Webpage Request for quotationCAS: 113873-67-9
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Product Name: Calcineurin Substrate Visit Supplier Webpage Request for quotation
CAS: 113873-67-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 113873-67-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History